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Mesothelioma and Asbestos Exposure Mesothelioma is a result of exposure to asbestos. The exposure could have occurred at work or at the home. Coughing, chest discomfort and a dry throat are all symptoms of pleural asbestosis. Other signs include abdominal pain, an accumulation of fluid and testicular cancer. There are four mesothelioma types. Pleural mesothelioma is the most prevalent type. Workplace Exposure Mesothelioma, a form of cancer that affects the tissues of certain organs, like the lungs and the abdomen, is typically caused by exposure to asbestos. This harmful mineral, which is utilized in a variety of industries, may cause fine dust to be inhaled and inhaled when it breaks down. In the past asbestos exposure was high in a variety of professions. This includes asbestos insulation plumbers, electricians, engineers, shipyard workers, and manufacturers of automotive parts, brake pads and clutches. Construction workers exposed to asbestos in their building materials, or when tearing down old buildings face a high chance of being exposed. When mesothelial cell mutations occur and they grow out of control, they may and cause tumors to are then spread throughout the body. Mesothelioma typically develops in the abdomen or lungs, but can also occur in other organs, like the testicles or the heart. There are a variety of kinds of mesothelioma and each one is named after the organ tissue it affects. The symptoms of mesothelioma typically show up 30 to 50 years after the first exposure. Mesothelioma is a rare cancer that is often difficult to identify and it may take a long time for the disease to manifest itself. Asbestos patients need medical assistance to determine the cause and receive treatment. Non-occupational asbestos exposure may increase mesothelioma risk. Indirect or secondary asbestos exposure is when people come into contact with fibers of asbestos through contaminated clothing or household items. The exposure can occur as family members clean someone's clothes or if they live near an industrial asbestos source. There aren't many population-based studies that have examined the para-occupational exposure to asbestos and mesothelioma risk. One study showed that people living near an asbestos cement factory in Casale Monferrato (northwest Italy) were at risk of developing mesothelioma. The authors attribute this increase due to the proximity of homes to the plant as well as exposure to airborne particles by asbestos cement products in the vicinity of roads and buildings. Similar results have been observed in other studies conducted by communities, which have clearly defined industrial sources of para-occupational exposure. However, these studies can be difficult to conduct. Some studies have had difficulty separating out individuals with known occupational or para-occupational exposure to asbestos, which can lead to them to make mistakes in assessing the mesothelioma dangers of these individuals. Environmental Exposure Asbestos is one of the minerals with thin microscopic fibers. Because they are invulnerable to chemical fires, as well as electricity, asbestos is utilized in a variety industrial processes and products. People who work with asbestos or are exposed in other ways have a higher chance of developing mesothelioma. This includes asbestos miners, shipyard workers as well as asbestos-cement producers and insulators. Mesothelioma also gets found in hair and clothing of asbestos workers, placing the family members at risk. The primary cause of mesothelioma lies in occupational exposure to asbestos. However, a small number of cases have been reported in patients who had non-occupational (para-occupational) exposure to asbestos. In these instances asbestos fibers could have gotten into the lungs or into the digestive tract through contaminated air or by eating a person's contaminated food. Fresno asbestos lawsuit of mesothelioma-related cases have occurred in the families of asbestos-exposed workers. The diagnosis of mesothelioma is typically made decades after asbestos exposure. The majority of mesothelioma tumors are found in the chest and abdomen. The most common type of mesothelioma is mesothelioma of the pleura which affects the lining of the chest cavity. The other most common mesothelioma type affects the abdominal cavity's lining known as the peritoneum. The mesothelioma cancer cells are classified as either epithelioid (epithelioid) or sarcomatoid (sarcomatoid). Between 60% and 70 percent of mesothelioma is epithelioid and has the best outcome. Sarcomatoid mesothelioma is more aggressive and has a lower prognosis. Biphasic mesothelioma, a type of meso that occurs in 10 to 15 percent of patients. It is a combination of epithelioid cells with sarcomatoid cells. Mesothelioma is more common in men than women, and most diagnosed with mesothelioma were exposed to asbestos via work-related exposure. However, the exact reasons behind this gender gap remain elusive. It is likely related to the fact that more men are employed in industries that frequently used asbestos, like construction and manufacturing. Multiple studies have shown that mesothelioma is more common in communities or areas with multiple asbestos-related sources. One study on mesothelioma within 70 communities that received contaminated Vermiculite from the Libby Asbestos Mine in Montana found that residents who lived within 2000 meters of these facilities had a higher risk of developing mesothelioma. Genetic Predisposition In some cases, genetics play a role in mesothelioma. The disease is believed to be related to hereditary mutations in genes that interfere with DNA repair mechanisms. Researchers have identified several genes that may lead patients to mesothelioma. Some studies have shown that people with mesothelioma-related family history are more likely to develop the disease than people without a family history. The mechanism behind the disease isn't fully understood. The disease can be caused by occupational and exposure to asbestos in the air. Not everyone exposed to asbestos will develop mesothelioma. Many mesothelioma victims have no asbestos exposure, while some individuals who have extensive occupational exposure do not develop the disease. Research suggests that these patients probably have genetic mutations that hinder normal DNA repair processes. A genetic mesothelioma test can be used to determine if an individual has the hereditary gene mutations that can increase their risk of developing the disease. The test can be performed by a doctor using the saliva sample or blood. The sample is sent to a laboratory for testing. The results of the test will usually be obtained within two weeks. Some families with multiple mesothelioma cases have BAP1 gene mutations. This gene is involved with the repair of damaged DNA. The mutation could cause cancerous cells to become over-produced and then spread to other parts of your body and lead to mesothelioma. Genetic mesothelioma tests can be a valuable method to identify asbestos-related diseases. They can aid doctors to understand the mesothelioma's root causes and create more effective treatment plans. The risk of exposure to asbestos is preventable by avoiding environmental and occupational exposure to the material. Anyone with mesothelioma in their family should talk to their physicians regarding the possibility of genetic risk. Some people may also benefit by participating in mesothelioma screening programs that require an swab of the cheek or blood sample. A group of experts assesses the mesothelioma diagnosis of a patient in these programs. The patient's mesothelioma treatment program is then developed in accordance with their specific diagnosis. Treatment Mesothelioma is a condition that occurs when asbestos fibers cause harm to the body, which leads to cancer. Asbestos can be exposed in a variety of ways, such as when workers break down asbestos to remove it or when people bring the asbestos fibers home on their skin and clothing after work. These fibers can enter the stomach and lungs where they can cause irritation, which leads to cancer. The signs of mesothelioma could not be evident for as long as 50 years after exposure. It is crucial that anyone who has been exposed to asbestos should consult their doctor right away. The majority of mesothelioma victims are men and the disease more commonly affects the linings of the lungs. Other types of mesothelioma can be found in the lining of the stomach the peritoneum, the lining of the heart or testicles. Like any other type of cancer, mesothelioma caused when cells grow in uncontrolled ways, eventually forming a tumor. The abnormal cells can then expand to other parts of the body, and eventually cause more cancerous tumors to form. Researchers are still unable to fully comprehend the causes of mesothelioma. However, they know that asbestos exposure is an important risk factor. Patients diagnosed with mesothelioma usually undergo surgery and chemotherapy to alleviate their symptoms and slow the progression of the disease. Anyone who has been exposed to asbestos should monitor their health and talk to their doctors about the work history. Mesothelioma victims should also be sure to undergo regular tests to check for evidence of exposure to asbestos and any other possible issues. The most common mesothelioma signs include discomfort and a buildup fluid around the lungs. Other signs include chest pain, coughing and a feeling of pressure on the chest and abdomen, abdominal swelling, difficulty breathing weight loss and fever. These symptoms may be similar to other illnesses and conditions which is why mesothelioma may be mistakenly diagnosed. Bloodwork, X-rays, and mesothelioma testing can help confirm the diagnosis. Some mesothelioma patients may also have genetic mutations in their DNA, which increases their chances of developing the disease. These patients should talk to their doctor about genetic counseling.